منابع مشابه
Creating Chances through Cognitive Niche Construction The Role of Affordances
As a matter of fact, humans continuously delegate and distribute cognitive functions to the environment to lessen their limits. They build models, representations, and other various mediating structures, that are considered to aid thought. In doing these, humans are engaged in a process of cognitive niche construction. In this sense, I argue that a cognitive niche emerges from a network of cont...
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O of the most apparent differences between normal cells and their malignantly transformed counterparts and between immature and fully differentiated cells is the shape of the cells (1). Cell morphology is controlled largely by the structure of the cytoskeleton, a system of three distinct types of filamentous polymers that assemble into networks and bundles of various kinds to link the cell inte...
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The self-renewal and differentiation properties of cancer stem cells (CSCs) are regulated and maintained by the CSC niche. However, the mechanism of this maintenance, especially the maintenance contributed by differentiated cancer cells, remains to be fully elucidated. Recently, we have established a model of CSCs, miPS-LLCcm, from mouse induced pluripotent stem cells (miPSCs). In vitro culture...
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The use of human embryonic stem cells (hESCs) for regeneration of the spiral ganglion will require techniques for promoting otic neuronal progenitor (ONP) differentiation, anchoring of cells to anatomically appropriate and specific niches, and long-term cell survival after transplantation. In this study, we used self-assembling peptide amphiphile (PA) molecules that display an IKVAV epitope (IK...
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Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have the capacity to differentiate into any specialized cell type of the human body, and therefore, ESC/iPSC-derived cell types offer great potential for regenerative medicine. However, key to realizing this potential requires a strong understanding of stem cell biology, techniques to maintain stem cells, and strategies to m...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2018
ISSN: 1600-6135
DOI: 10.1111/ajt.15139